Deeks Clinical Research Group
University of California San Francisco, San Francisco, CA
In collaboration with the SCOPE cohort, led by Dr. Steven Deeks and Dr. Jeffrey Martin, we conduct patient-oriented cohort and interventional trials. Dr. Deeks leads the DARE UM1 Martin Delaney Collaboratory as well as is on the leadership committee for the amfAR UCSF HIV Cure Institute, two large efforts to develop curative interventions for HIV disease.
Sekaly Lab
Emory University, Atlanta GA
In collaboration with the Sekaly lab, we are investigating the immunologic signatures associated with HIV+ individuals by performing high throughput transcriptomics analyses in individuals with unique HIV+ phenotypes. Dr. Sekaly is Co-Director of the Proteomics and Systems Biology Core at Emory University and has over 30 years of experience in immunologic research identifying the molecular mechanisms regulating the human immune response.
Roan Lab
University of California San Francisco, San Francisco, CA
Gladstone Institute of Virology and Immunology
In collaboration with the Roan lab, we are investigating the immunologic signatures associated with HIV+ long-term non-progressors by performing high dimensional mass cytometry (CyTOF) from lymph node aspirate samples.
Kiem and Jerome Labs
Fred Hutchinson Research Center/University of Washington, Seattle, WA
In collaboration with the Jerome lab, we are performing HIV sequencing into host genomes of HIV+ ART-suppressed individuals and linked to measures of HIV latency.
Hartigan-O'Connor Lab
University of California Davis, Davis, CA
In collaboration with the Hartigan-O’Connor lab, we performed a preclinical non-human primate study demonstrating that kansui, a botanical product, was well tolerated in rhesus macaques and resulted in increased markers of immune activation and viral transcription.
Spivak Lab
University of Utah, Salt Lake City, Davis, Davis, CA
In collaboration with the Spivak lab and the University of Utah HIV clinical team, we are conducting a phase I randomized, placebo-controlled crossover trial in HIV+ ART-suppressed individuals, testing kansui, a botanical product that has been shown ex vivo to reactivate virus.
Kroetz Lab
University of California San Francisco, San Francisco, CA
In collaboration with the Kroetz lab, we are performing a genome-wide association study of host genetic predictors of CD4+ T cell recover in HIV+ Ugandans initiating ART.
Wang Lab
University of California Berkeley, Berkeley, CA
In collaboration with Jingshen Wang, Lei Shi, and Junzhe Shao we are analyzing longitudinal cytokine data and reservoir measurements associated with our acute HIV+ cohort. Dr. Jingshen Wang is an Assistant Professor in Biostatistics at the School of Public Health at Berkeley and is currently applying machine-learning methods to genetic datasets to assess the efficacy of lifestyle interventions. Lei Shi and Junzhe Shao are PhD students in Biostatistics at the School of Public Health at Berkeley and are currently working on high-dimensional statistics, causal inference, and learning theory.
Ioannidis Lab
University of California Berkeley, Berkeley, CA
In collaboration with Nilah Monnier Ioannidis and Ryan Chung, we are conducting whole genome-wide sequencing to investigate HIV cardiovascular risk associated with the NLRP3 pathway and identify potential novel mechanisms by which individuals have high interleukin-1β levels after ART initiation. Dr. Nilah Monnier Ioannidis is an Assistant Professor in the Electrical Engineering & Computer Sciences (Computational Biology) Department and Center for Computational Biology (CCB), and Ryan Chung is a PhD student at the CCB. At the Ioannidis Lab, they are currently applying machine-learning and biocomputational methods for interpreting genetic variation with transcriptome variation to understand clinical relationships and predict disease risks.
Hladik Lab
University of Washington, Seattle, WA
In collaboration with Florian Hladik, German Gornalusse, and Phuong “Luna” N Vo, we are evaluating host genomic and transcriptomic predictors of the HIV reservoir. Dr. Florian Hladik is a research professor at the Obstetrics and Gynecology Department and Division Chief of the Clinical Research Division, Dr. German Gornalusse is a research assistant professor at the Obstetrics and Gynecology Department, and Luna Vo is a research assistant at the Hladik lab. At their lab, they apply genomics and mucosal immunology to study the pathogenesis of HIV and identify novel strategies for HIV cure.